פרופ' סיגל זלכה-מנו

1. Zilcha-Mano, S. (2025). Therapeutic change may begin before the therapist and patient ever meet: Pre-treatment alliance changes predict clinical outcomes. Psychotherapy and Psychosomatics 2. Zilcha-Mano, S., #Tchizick, A., Nof, A., #Malka, M., & Oded, Y. Clinical breakthroughs or research oversights? The imperative of integrating modalities to differentiate signal from noise. BJPsych. 3. Zilcha-Mano, S. (2025). A glance into the future of artificial intelligence-enhanced scalable personalized training: A response to Kopelovich, Brian, et al.(2025) and Kopelovich, Slevin, et al.(2025).‏ 4. Zilcha-Mano, S., #Bouknik, Y., #Malka, M., & Krasovsky, T. (2025). An individual-specific understanding of how synchrony becomes curative: Study protocol. BMC Psychiatry. 5. Zilcha-Mano, S. (2025). Almost ninety years of common factors: Are they still useful in research and practice? Journal of Consulting and Clinical Psychology. 6. Zilcha-Mano, S. (2025). Contrasting individual-specific resilience and compensation personalization frameworks: The case of rumination. Biological Psychiatry: Global Open Science 7. Zilcha-Mano, S. Is Targeting Depression Sufficient to Alleviate Anxiety Comorbidity? Exploring Between-Individual Heterogeneity in Within-Individual Processes. (2025). Clinical Psychological Science. 8. # Fisher, H., Reiss, P. T., Atias, D., # Malka, M., Shahar, B., Shamay-Tsoory, S., & Zilcha Mano, S. (2025). Facing emotions: Between- and within-session changes in facial expression during psychological treatment for depression. Clinical Psychological Science. 9. Zilcha-Mano, S. (2025). We need to personalize (mental) health, not only psychopathology. Journal of Psychopathology and Clinical Science. 10. Zilcha-Mano, S. (2025). How getting in sync is curative: Insights gained from research in psychotherapy. Psychological Review. 11. Zilcha-Mano, S. (2025). Individual-specific animated profiles of mental health. Perspectives on Psychological Science. 12. Zilcha-Mano, S., & Krasovsky, T. (2025). Using virtual reality to understand mechanisms of therapeutic change. Nature Reviews Psychology. 13. Zilcha-Mano S, Duek O, Suarez-Jimenez B, Zhu X, Lazarov A, Helpman., # Malka, M. & Neria, Y. (2023). Underlying hippocampal mechanism of PTSD-treatment outcome: Evidence from two clinical trials. Biological Psychiatry: Global Open Science. 3(4), 867–874. 14. # Bar-Sella, A. # Nof, A., Baucom, B., Kaplun, D., Romanov, S., Goldstein, P., Shpakouskaya, I., & Zilcha-Mano, S. (2023). The prognostic role of emotion regulation dynamics in the treatment of major depressive disorder. Journal of Consulting and Clinical Psychology. 15. Zilcha-Mano, S. & Webb, C.A. (2023). Identifying who benefits most from supportive vs. expressive techniques in psychotherapy for depression: Moderators of within- vs. between-individual effects. Journal of Consulting and Clinical Psychology. APA’s Editor’s Choice article. 16. Zilcha-Mano, S., # Keefe, J. R., # Fisher, H., # Veler-Poleg, N., # Dolev-Amit, T., & Barber, J. P. (2023). Is the use of interpretations associated with treatment outcome? A systematic review and meta-analytic answer. Clinical Psychology: Science and Practice.‏ 17. Zilcha-Mano, S. Goldstein, P., # Dolev-Amit, T., # Ben David-Sela, T., & Barber, J.P. (2022). A randomized controlled trial for identifying the most suitable treatment for depression based on patients’ attachment orientation. Journal of Consulting and Clinical Psychology, 89(12), 985-994. 18. Zilcha-Mano, S., & # Fisher, H. (2022). Distinct roles of state-like and trait-like patient-therapist alliance in psychotherapy. Nature Reviews in Psychology, 1. 19. Zilcha-Mano, S., Zhu, X., Lazarov, A., Suarez-Jimenez, B., Helpman, L., Kim, Y., Maitlin, C., Neria, Y., & Rutherford, B. (2022). Structural brain features signaling trauma, PTSD, or resilience? A systematic exploration. Depression and Anxiety, 39, 695-705. 20. # Cohen, K., # Tal, S., Ramseyer, F.T., & Zilcha-Mano, S. (2021). The association between motion synchrony and alliance is more complex than we thought: Disentangling the state-like and trait-like effects of the alliance. Clinical Psychological Science, 9(4), 634-648. 21. Zilcha-Mano, S. (2021). Toward personalized psychotherapy: The importance of the trait-like / state-like distinction for understanding therapeutic change. American Psychologist, 76(3), 516-528. 22. Zilcha-Mano, S., Goldstein, P., # Dolev, T., & Shamay-Tsoory, T. (2021). Oxytocin synchrony between patients and therapists as a mechanism underlying effective psychotherapy for depression. Journal of Consulting and Clinical Psychology, 89(1), 49-57. 23. Zilcha-Mano, S., Shahar, B., # Fisher, H., # Dolev-Amit, T., Greenberg, L. S., & Barber, J. P. (2021). Investigating patient-specific mechanisms of change in SET vs. EFT for depression: study protocol for a mechanistic randomized controlled trial. BMC psychiatry, 21(1), 1-11. 24. Zilcha-Mano, S., Wallace, M., Brown, P., Sneed, J., Roose, S., & Rutherford, R. (2021). Who benefits most from expectancy effects? A combined neuroimaging and antidepressant trial in depressed older adults. Translational Psychiatry, 11(1), 1-5.‏ 25. Zilcha-Mano, S. & Ramseyer, F.T. (2020). Innovative approaches to exploring processes of change in counseling psychology: Insights and guidelines for future research. Journal of Counseling Psychology, 67(4), 409-419. 26. Zilcha-Mano, S., Zhu, X., Suarez-Jimenez, B., Pickover, A., Such, S., Marohasy, C., # Tal, S., Chrisanthopoulos, M., Salzman, C., Lazarov, A., Neria, Y., & Rutherford, B. (2020). Diagnostic and predictive neuroimaging biomarkers for posttraumatic stress disorder: A machine learning study. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, 5(7), 688-696. 27. Zilcha-Mano, S. (2019). Major developments in methods addressing for whom psychotherapy may work for and why. Psychotherapy Research, 29(6), 693-708. 28. Zilcha-Mano, S., Eubanks, C. F., & Muran, C. J. (2019). Sudden gains in the alliance in cognitive behavioral therapy vs. alliance-focused therapy. Journal of Consulting and Clinical Psychology, 87, 501-509. 29. Zilcha-Mano, S., Errázuriz, P., # Yaffe, L., German, R.E., & DeRubeis, R.J. (2019). Are there any robust predictors of "sudden gainers," and how is sustained improvement in treatment outcome achieved following a gain? Journal of Consulting and Clinical Psychology, 87(6), 491-500. 30. Zilcha-Mano, S. (2017). Is alliance really therapeutic? A systematic answer based on recent methodological developments. American Psychologist, 72(4), 311–325.

• מה גורם לטיפול להיות אפקטיבי?
• איך אפשר להגדיל אפקטיביות דרך התאמת הטיפול למאפייני וצרכי האינדיבידואל הספציפי?
• איך סינכרון מולטי-מודלי משפיע על הצלחת הטיפול
• איך ניתן דרך מערכות פידבק מתקדמות להשפיע על הצלחת הטיפול דרך הבנה של סינכרון מולטי-מודלי?

● SELECTED FELLOWSHIPS AND AWARDS (out of 26)
2025 Humboldt Research Award (€80,000)
2025 Member, National Academy of Sciences (Israel)
2025 Best Scientific Paper for 2024, American Psychoanalytic Association ($1,000)
2024 University of Haifa 2024 Mid-Career Research Excellence Award (10,000 NIS)
2020 Early Career Award, The International Society for the Exploration of Psychotherapy Integration ($1,000)
2019 American Psychological Association (APA) – Fellow status
2019 Early Career Award, American Psychological Association (APA), Division 29 ($1,600)
2016 Outstanding Early Career Achievement Award, the International Society for Psychotherapy Research (SPR).
2015 Dusty and Ettie Miller Fellowship for Outstanding Young Scholars ($10,000)
2014 The Lady Davis Fellowship Trust, the Hebrew University (declined)
2013 Fulbright Alumni Prize, psychotherapy research ($2,500)
2012 Fulbright Post-Doctoral Scholar Award, psychotherapy research ($37,500).
2007 University's president's grant for special distinction, Bar Ilan University ($40,000)
2006 Wolf Award for special distinction, Tel Aviv University ($4,000)
2005 Dangoor Award for special distinction, Bar Ilan University ($4,000)
2003 Dean’s Award, Ben Gurion University ($4,000)
2002 Dean’s Award, Ben Gurion University ($4,000)

לא פחות חשוב - פרופ' סיגל זלכה-מנו נהנת מאוד מבילויים עם משפחתה, וכן מכל סוגי הספורט בחיק הטבע ובכלל, ובמיוחד - מריצה, רכיבה על אופני שטח וכביש, ושחייה